Atomistic description of conformational changes in proteins from pico to millisecond timescales

Atomistic description of conformational changes in proteins from pico to millisecond timescales

Virtual screens and de-novo ligand design via free energy calculations

Virtual screens and de-novo ligand design via free energy calculations

Rational ligand design by modulation of protein dynamics

Rational ligand design by modulation of protein dynamics

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Research in the Michel lab is focussed on quantitative description of protein-ligand interactions. This is pursued through development of biomolecular simulation software and algorithms, and biophysical measurements to characterise the structure, dynamics and thermodynamics of protein-ligand interactions. 

Currently

Latest News

Welcome to new group members

20 October 2026
Welcome to new group members

  With the new academic year in full swing it was high time to update the group photo ! Welcome to new team members   PhD student Anahita Manchala -...

Group updates

05 May 2025

Two group members recently moved on to other pastures. Congratulations to Finlay who passed his PhD viva last month (unfortunately we were all so distracted that we forgot to take...

Wellcome to Silvia

04 February 2025

  The group is happy to host visiting PhD student Silvia Menin from the University of Padova. Silvia is working in the group of Prof. Stefano Moro in collaboration with...

Young Modellers Forum 2024

02 December 2024

Congratulations to Finlay Clark for winning a prize for his talk on ''Automated Adaptive Absolute Binding Free Energy Calculations'' at the 28th Young Modellers Forum meeting in Oxford, November 29th...

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Meet our group members